Math Puzzle 7

Puzzle 1: What number replaces the question mark?

Puzzle 2: what does the below mathematical rebus means?

Puzzle 3: What number replaces the question mark?

Puzzle 4: What number replaces the question mark?

5, 7, 11, 13, 17, ?

Puzzle 5: What number replaces the question mark?

IF 1 + 1 = 5

2 + 2 = 20

3 + 3 = 45

Then, 4 + 4 =?